Mucuna pruriens extract

Mucuna Pruriens (MP), which is used in Ayurveda medicine today, is a wild natural legume that grows in the tropical regions of the world. It is readily available worldwide. Its beans (seeds) contain between 3-7% of naturally occurring L-Dopa which is a precursor to the hormone neurotransmitter dopamine. Dopamine effects mood and motivation, and is vital to hormonal balance, good health, and a strong immunity. There are over 60,000 research studies on L-Dopa, with many focused on the benefits of L-Dopa extracted from Mucuna Pruriens. Our MP extract is tested several times through the manufacturing process for heavy metals, pesticides, and biologic contaminants.

Ayurveda (sounds like “air-u-v-dah”) or more formally known as ayurvedic (sounds like “air-u -veh-dic”) medicine is one of the oldest healing systems in the world that was developed more than 30 centuries ago in India. It is a “holistic” (whole body) treatment approach to overall health and well-being through the use of safe natural substances found in nature. Its main goal is to provide good health, not fight or treat specific diseases. Mucuna Pruriens was used by Hippocrates, who is considered the father of medicine.

Red Clover

Red Clover (Trifolium pratense) extract provides a source of each critical isoflavone (formononetin, biochanin A, genistein, and diadzein) employed to promote the shift in the human steroidal hormone cascade away from cortisone and aldosterone, and toward adiols, estradiol, and testosterone – to have a profound beneficial effect on the steroidal pathway. These isoflavons are also anti-inflammatory and tend to couple to the same receptor sites and anti-inflammatory hormones in the cascade, thereby reducing the need for endogenous biosynthesis and allowing a shift in hormonal synthesis away from these hormones toward the lower end of the steroidal cascade.

Studies show that the isoflavones increase the body’s innate and adaptive natural immunity response to pathogens in fighting bacterial and viral infections. There are also studies that show that the ability of the body to repair and heal itself is increased.

Alpha-lipoic Acid

Highest quality alpha-lipoic acid is used in a form that offers high potency and physiological availability and acts as a cofactor for enzyme complexes. We are committed to raw materials that are ORGANIC, Sustainable, and non-GMO. Alpha Lipoic acid is critical to hundreds of millions of simultaneous metabolic functions within the body. Without it you could not live. There is a very large body of knowledge that has been developed around the function of Alpha Lipoic Acid. It is listed on the old dietary ingredients list, although it is important to understand that the FDA has yet to finalize that list. Some studies suggest Alpha Lipoic Acid impacts mitochondrial function which is critical for intra cellular signaling within the cell. Many people buy it for its antioxidant qualities. It is also suggested that Alpha Lipoic acid has a favorable impact on Reactive Oxidative Stress. We use the highest quality Alpha Lipoic Acid available. As with all our active ingredients used to formulate ZADIOL™, it is tested immediately upon receipt by our labs to verify the Certificate of Analysis is accurate. And these test results are compared to our requirements for safety, purity, and potency before the product is placed into processing.

Red Clover and Isoflavones FAQs

What is Red Clover Extract?

Red Clover, known scientifically as Trifolium Pratense, is an herbaceous species of flowering plant in the bean family Fabaceae — native to Europe, Western Asia, and northwest Africa, but planted and naturalized in many other regions around the world, including North America. The plant’s flowers contain isoflavones, and we use an extract that is produced by a laboratory in Switzerland using a sophisticated patented process to reduce the fiber and increase the nutritional benefits of Red Clover. Learn more about how ZADIOL™ works.

How long have people taken Red Clover for its benefits?

Red Clover has been consumed and used in traditional medicinal remedies in Asia, Europe, and other parts of the world for over 35 centuries.

What are Isoflavones?

Isoflavones are a group of natural molecules referred to as phytochemicals or natural plant chemicals. These molecules are almost exclusively found in the Fabaceae (Leguminosae or bean) family and in the herb Red Clover. There are many potential health benefits from taking isoflavones as they are considered a type of nutritional supplement and are sometimes considered phytoestrogens, meaning that they are similar in structure to the female hormone, estrogen.

What are the benefits of Isoflavones?

Isoflavones are considered powerful anti-oxidant compounds that reduce damage due to oxygen and free radicals. The harmful activities of free radicals are associated with damage to membranes, enzymes, and DNA. The ability of antioxidants to destroy free radicals protects the structural integrity of cells and tissues, which is important in maintaining a strong immune system.

Are Isoflavones safe for women that have a family history of breast cancer?

Yes, a three-year study supports the growing body of evidence that treatment with red clover isoflavones is safe and well tolerated in healthy women. Supplements containing red clover isoflavones did not adversely affect breast density, skeletal strength, or cardiovascular status.

Have Red Clover Isoflavones been researched by scientists?

A recent Google search for “clinical studies on red clover isoflavones” provided a result of 7,860 articles. A wider Google search for “clinical studies on isoflavones” resulted in 56,000 articles! Isoflavones have been extensively studied for years and the research is continuously expanding.

Does Red Clover make you gain weight?
No, there are no conclusive studies that clearly indicate that phytoestrogens caused a weight gain in the participants of the study.

Phytoestrogen and Estrogen FAQs

What are Phytoestrogens that are in ZADIOL™?

Phytoestrogens are trace biochemicals produced by plants that act like estrogens in cells and bodies. They have structures that are very similar to endogen estradiol derived from plants. Essentially, they are plant hormones. These healthy beneficial chemical compounds naturally occur in plants and have weak estrogenic properties when compared to estrogens that are produced in the human body. Phytoestrogens are not the same as estrogens, although they are similar because of the receptor affinity to bind beta estrogen receptors in the body.

Do men and women produce Phytoestrogens?
No, phytoestrogens are only produced in plants. The human body does not produce phytoestrogens.
Are taking the Phytoestrogens in ZADIOL™ a benefit to men and women?

Although still inconclusive, scientific evidence is accumulating to suggest that phytoestrogens may have a role in preventing chronic disease in both men and women. A clinical resource article published in U.S. Pharmacist titled “Focus on Phytoestrogens” is a researcher’s resource document on the benefits of phytoestrogens in maintaining good health and preventing disease. It is an excellent starting point in source information for the summary of clinical data on the beneficial impact phytoestrogens have on health, and time has proven most of the information to be supported by subsequent studies since it was published in December 2007.

Do men and women produce Estrogen naturally?

Yes, while females tend to have higher estrogen levels, it is a sex hormone produced naturally in both males and females. The ovaries, testes, fat cells, and adrenal glands all produce the estrogen hormone.

Are balanced Estrogen levels important in men?

Yes, recent studies find that estrogen is very important for men. Although it is considered a ‘female hormone,’ all bodies produce estrogen. A healthy balance of estrogen and testosterone is important for sexual growth and development, as well as many immunity metabolic functions. When these hormones become imbalanced, immunity and sexual development or function may be adversely affected. Balanced estrogen levels contribute to cognitive health, bone health, the function of the cardiovascular system, immunity, and other essential bodily processes.

Are balanced Estrogen levels important in women?

Yes, estrogen is important for women and the reproductive system. Balanced estrogen levels contribute to cognitive health, bone health, the function of the cardiovascular system, immunity, and other essential bodily processes.

Is Estradiol the same as Estrogen?

Estriol (E3) and estradiol (E2) are two different forms of the female hormone known as estrogen (sometimes referred to as oestrogen). These forms of estrogen are steroid hormones that are naturally found in the body. Estriol and estradiol can be used as hormone replacement therapy (HRT) for women after menopause. (THE CHECKUP by SingleCare - Jan 22, 2020)

Are Phytoestrogens safe?

Yes, there are thousands of clinical trials that indicate no observable serious adverse effects from phytoestrogens. Red Clover is listed as an ancient dietary ingredient that has been used in Ayurvedic medicine for over 3,500 years and is widely available commercially.

Have Phytoestrogens been researched by scientists?

Yes, on Google the search term “scientific studies on phytoestrogens” results in 29,200 articles. There are tens of thousands of scientific articles found throughout the world conducted by hundreds of thousands of researchers.

Is there credible historical scientific data on the benefit of Phytoestrogens?

Yes, and the scientific evidence is accumulating that supports the benefits of phytoestrogens. In Google, the search term “scientific studies phytoestrogens benefits” produces 22,800 articles. Many of these studies followed accepted rigorous scientific methods.